Natural Menthol Crystals
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Natural Menthol Crystals

Natural Menthol Crystals has many functions and functions. Natural Menthol Crystals can be used to make toothpaste and toilet water. Sometimes,Natural Menthol Crystals can be added to perfume. In addition, Natural Menthol Crystals also has anti-itching effect, and the skin is very cool after use.Natural Menthol Crystals can also be used to treat headache, nose, pharynx, throat inflammation, etc., so Natural Menthol Crystals is widely used in medicine.

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Product Description

Natural Menthol Crystals Basic information
Product Name: Natural Menthol Crystals
Synonyms: (1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol;(1r,3r,4s)-(-)-mentho;(1R,3R,4S)-(-)-MENTHOL;(R)-(-)-Menthol;Emtricitabine Impurity 31;Natural Menthol Crystal;L-Meng alcohol Natural menthol Menthol (L);DL-Menthol menthol crystal extract
CAS: 2216-51-5
MF: C10H20O
MW: 156.27
EINECS: 218-690-9
Product Categories: Inhibitors;Organics;chiral;API;Biochemistry;Terpenes;Terpenes (Others);for Resolution of Acids;Monocyclic Monoterpenes;Optical Resolution;Synthetic Organic Chemistry
Mol File: 2216-51-5.mol
L-Menthol Structure
Natural Menthol Crystals Chemical Properties
Melting point  41-44 °C(lit.)
alpha  -51 º (589nm, c=10, EtOH)
Boiling point  212 °C(lit.)
density  0.89 g/mL at 25 °C(lit.)
vapor pressure  0.8 mm Hg ( 20 °C)
FEMA  2665 | MENTHOL RACEMIC
refractive index  1.46
Fp  200 °F
storage temp.  −20°C
solubility  490mg/l
form  Crystals or Crystalline Needles
pka 15.30±0.60(Predicted)
color  Colorless to white
Specific Gravity 0.89
optical activity [α]22/D 49°, c = 10 in 95% ethanol
Water Solubility  insoluble
Merck  14,5837
BRN  1902293
Stability: Stable.
InChIKey NOOLISFMXDJSKH-KXUCPTDWSA-N
CAS DataBase Reference 2216-51-5(CAS DataBase Reference)
NIST Chemistry Reference Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1«alpha»,2«beta»,5«alpha»)]-(2216-51-5)
EPA Substance Registry System Levomenthol (2216-51-5)
Natural Menthol Crystals Safety Information
Hazard Codes  Xi
Risk Statements  37/38-41-36/37/38
Safety Statements  26-39-37/39-36
WGK Germany  2
RTECS  OT0700000
TSCA  Yes
HS Code  29061100
Hazardous Substances Data 2216-51-5(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 3300 mg/kg LD50 dermal Rabbit > 5000 mg/kg
Natural Menthol Crystals MSDS Information
Provider Language
(1R,2S,5R)-(-)-Menthol English
SigmaAldrich English
ACROS English
ALFA English
Natural Menthol Crystals Usage And Synthesis
Chemical Properties white to light yellow crystal powde
Uses analgesic (topical), antipruritic agent
Uses (1R,2S,5R)-(-)-Menthol (L-Menthol) is the natural form of Menthol. L-Menthol is used as: refreshing agent, food flavor, cool and antipruritic drug, carminative drug. Menthol crystals is used for pers onal care and cosmetics.
Definition ChEBI: A p-menthan-3-ol which has (1R,2S,5R)-stereochemistry. It is the most common naturally occurring enantiomer.
Safety Profile Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. An eye irritant. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods Crystallise menthol from CHCl3,pet ether or EtOH/water. [Barrow & Atkinson J Chem Soc 638 1939, Beilstein 6 III 133, 6 IV 150.]
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