Natural Menthol Crystals has many functions and functions. Natural Menthol Crystals can be used to make toothpaste and toilet water. Sometimes,Natural Menthol Crystals can be added to perfume. In addition, Natural Menthol Crystals also has anti-itching effect, and the skin is very cool after use.Natural Menthol Crystals can also be used to treat headache, nose, pharynx, throat inflammation, etc., so Natural Menthol Crystals is widely used in medicine.
| Natural Menthol Crystals Basic information |
| Product Name: | Natural Menthol Crystals |
| Synonyms: | (1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol;(1r,3r,4s)-(-)-mentho;(1R,3R,4S)-(-)-MENTHOL;(R)-(-)-Menthol;Emtricitabine Impurity 31;Natural Menthol Crystal;L-Meng alcohol Natural menthol Menthol (L);DL-Menthol menthol crystal extract |
| CAS: | 2216-51-5 |
| MF: | C10H20O |
| MW: | 156.27 |
| EINECS: | 218-690-9 |
| Product Categories: | Inhibitors;Organics;chiral;API;Biochemistry;Terpenes;Terpenes (Others);for Resolution of Acids;Monocyclic Monoterpenes;Optical Resolution;Synthetic Organic Chemistry |
| Mol File: | 2216-51-5.mol |
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| Natural Menthol Crystals Chemical Properties |
| Melting point |
41-44 °C(lit.) |
| alpha | -51 º (589nm, c=10, EtOH) |
| Boiling point |
212 °C(lit.) |
| density |
0.89 g/mL at 25 °C(lit.) |
| vapor pressure |
0.8 mm Hg ( 20 °C) |
| FEMA | 2665 | MENTHOL RACEMIC |
| refractive index | 1.46 |
| Fp |
200 °F |
| storage temp. |
−20°C |
| solubility | 490mg/l |
| form | Crystals or Crystalline Needles |
| pka | 15.30±0.60(Predicted) |
| color | Colorless to white |
| Specific Gravity | 0.89 |
| optical activity | [α]22/D 49°, c = 10 in 95% ethanol |
| Water Solubility | insoluble |
| Merck | 14,5837 |
| BRN | 1902293 |
| Stability: | Stable. |
| InChIKey | NOOLISFMXDJSKH-KXUCPTDWSA-N |
| CAS DataBase Reference | 2216-51-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1«alpha»,2«beta»,5«alpha»)]-(2216-51-5) |
| EPA Substance Registry System | Levomenthol (2216-51-5) |
| Natural Menthol Crystals Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41-36/37/38 |
| Safety Statements | 26-39-37/39-36 |
| WGK Germany |
2 |
| RTECS |
OT0700000 |
| TSCA | Yes |
| HS Code | 29061100 |
| Hazardous Substances Data | 2216-51-5(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 3300 mg/kg LD50 dermal Rabbit > 5000 mg/kg |
| Natural Menthol Crystals MSDS Information |
| Provider | Language |
|---|---|
| (1R,2S,5R)-(-)-Menthol | English |
| SigmaAldrich | English |
| ACROS | English |
| ALFA | English |
| Natural Menthol Crystals Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde |
| Uses | analgesic (topical), antipruritic agent |
| Uses | (1R,2S,5R)-(-)-Menthol (L-Menthol) is the natural form of Menthol. L-Menthol is used as: refreshing agent, food flavor, cool and antipruritic drug, carminative drug. Menthol crystals is used for pers onal care and cosmetics. |
| Definition | ChEBI: A p-menthan-3-ol which has (1R,2S,5R)-stereochemistry. It is the most common naturally occurring enantiomer. |
| Safety Profile | Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. An eye irritant. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. |
| Purification Methods | Crystallise menthol from CHCl3,pet ether or EtOH/water. [Barrow & Atkinson J Chem Soc 638 1939, Beilstein 6 III 133, 6 IV 150.] |
